Periodontal Inflammation

  • Thursday 1/27/2022
  • Time: 8:00 - 11:00 am
  • Course Code: 112TL
  • Cost: $99
  • Room Location: BCEC Room 106
  • Credits: 3 CE Hours
Thomas Van Dyke, DDS, PhD is a diplomate of the American Board of Periodontology and chair for the department of periodontology at the Forsyth Institute in Cambridge, MA.

Recent studies have suggested that periodontal disease is an inflammatory disease initiated by bacterial biofilm that leads to sustained inflammation and microbiome dysbiosis; it is an infectious inflammatory disease. If untreated, dysbiosis of the oral microbiome results in more inflammation further amplifying the dysbiosis establishing a progressive inflammatory cascade. This distinction implies that it is the host response to the biofilm that destroys the periodontium in the pathogenesis of the disease. This paradigm shift has broad implications for the prevention and treatment of periodontitis. As our understanding of pathways of inflammation has matured, a better understanding of the molecular basis of resolution of inflammation, which is distinct from pharmacologic anti-inflammation, has emerged. Resolution of inflammation is an active; receptor agonist mediated well-orchestrated return of tissue homeostasis, not inhibition of proinflammatory pathways. The isolation and characterization of endogenous lipid mediators of resolution, called lipoxins and resolvins, has open new doorways for the management of periodontitis including periodontal regeneration. This course will review resolution of inflammation in the context of periodontal disease and clarify the role of bacteria in periodontitis, explore therapeutic targets and update development of new therapeutics.

After this course attendees will be able to:
  • Identify the relationship between inflammation, bone loss, and tissue regeneration in periodontitis
  • Explain the mechanism of action of periodontal regeneration; why it works, and doesn’t work in different situations
  • Discuss potential modifications of treatment regimens for the patient with periodontitis to control inflammation, prevent further damage, and achieve true periodontal regeneration
  • Analyze the biologic basis of the relationship between periodontitis and systemic disease
  • Develop a working knowledge of inflammatory interactions leading to and linking the common diseases of aging
  • Understand the modifications of treatment for the patient with periodontitis and complicating systemic disease
Recommended Audience: Dentist, Hygienist